Bayesian Experimental Design of Magnetic Resonance Imaging Sequences
Matthias Seeger · Hannes Nickisch · Rolf Pohmann · Bernhard Schölkopf

Tue Dec 9th 09:52 -- 09:53 AM @ None

We show how improved sequences for magnetic resonance imaging can be found through automated optimization of Bayesian design scores. Combining recent advances in approximate Bayesian inference and natural image statistics with high-performance numerical computation, we propose the first scalable Bayesian experimental design framework for this problem of high relevance to clinical and brain research. Our solution requires approximate inference for dense, non-Gaussian models on a scale seldom addressed before. We propose a novel scalable variational inference algorithm, and show how powerful methods of numerical mathematics can be modified to compute primitives in our framework. Our approach is evaluated on a realistic setup with raw data from a 3T MR scanner.

Author Information

Matthias Seeger (Amazon)
Hannes Nickisch (Philips Research)
Rolf Pohmann (Max-Planck-Institute for biologicals Cybernetics)
Bernhard Schölkopf (MPI for Intelligent Systems)

Bernhard Scholkopf received degrees in mathematics (London) and physics (Tubingen), and a doctorate in computer science from the Technical University Berlin. He has researched at AT&T Bell Labs, at GMD FIRST, Berlin, at the Australian National University, Canberra, and at Microsoft Research Cambridge (UK). In 2001, he was appointed scientific member of the Max Planck Society and director at the MPI for Biological Cybernetics; in 2010 he founded the Max Planck Institute for Intelligent Systems. For further information, see

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