Memory Reactivation in Awake and Sleep States
Matthew Wilson
2013 Invited Talk
Abstract
By introducing arrays of microelectrodes into hippocampal, thalamic, and neocortical areas of freely behaving rodents, we have characterized the detailed structure and content of memory patterns across ensembles of individual neurons as they are formed during spatial behavior, and reactivated during quiet wakefulness, and sleep. I will describe the contributions of these brain systems to the expression and coordination of memory reactivation, including recent results demonstrating the ability to influence reactivated memory content during sleep.
Speaker
Matthew Wilson
Matthew Wilson received his bachelor’s degree in Electrical Engineering from Rensselaer Polytechnic Institute in 1983, his master’s degree in Electrical Engineering from the University of Wisconsin, Madison in 1986, and his Ph.D. in Computation and Neural Systems from the California Institute of Technology in 1990. In 1991 he began his work studying the formation of memory in the hippocampus using large-scale multiple electrode recording of neuronal ensembles in the hippocampus of freely behaving rats at the University of Arizona, Tucson. He continues to study the mechanisms of memory formation in the rodent at the Massachusetts Institute of Technology as a member of the faculty of the Departments of Brain and Cognitive Sciences, and Biology, the Picower Center for Learning and Memory, and the RIKEN-MIT Neuroscience Research Center.
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