Abstract: This paper presents innovative enhancements to diffusion models by integrating a novel multi-resolution network and time-dependent layer normalization.Diffusion models have gained prominence for their effectiveness in high-fidelity image generation.While conventional approaches rely on convolutional U-Net architectures, recent Transformer-based designs have demonstrated superior performance and scalability.However, Transformer architectures, which tokenize input data (via "patchification"), face a trade-off between visual fidelity and computational complexity due to the quadratic nature of self-attention operations concerning token length.While larger patch sizes enable attention computation efficiency, they struggle to capture fine-grained visual details, leading to image distortions.To address this challenge, we propose augmenting the **Di**ffusion model with the **M**ulti-**R**esolution network (DiMR), a framework that refines features across multiple resolutions, progressively enhancing detail from low to high resolution.Additionally, we introduce Time-Dependent Layer Normalization (TD-LN), a parameter-efficient approach that incorporates time-dependent parameters into layer normalization to inject time information and achieve superior performance.Our method's efficacy is demonstrated on the class-conditional ImageNet generation benchmark, where DiMR-XL variants surpass previous diffusion models, achieving FID scores of 1.70 on ImageNet $256 \times 256$ and 2.89 on ImageNet $512 \times 512$. Our best variant, DiMR-G, further establishes a state-of-the-art 1.63 FID on ImageNet $256 \times 256$.